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human umbilical cord-derived mesenchymal stem cells (Puren Hospital)
- Development stage
- Unknown
- Lead developer
- Puren Hospital Affiliated to Wuhan University of Science and Technology
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Human umbilical cord-derived mesenchymal stem cells (UC-MSCs) is an investigational cell therapy developed by Puren Hospital Affiliated to Wuhan University of Science and Technology for the treatment of COVID-19 pneumonia. These allogeneic, non-hematopoietic stem cells possess potent immunomodulatory, anti-inflammatory, and tissue-regenerative properties. When administered intravenously, UC-MSCs are thought to home to the lungs and secrete a variety of bioactive factors (paracrine signaling) that suppress the overactive immune response (cytokine storm) and promote the repair of damaged alveolar tissue, thereby improving respiratory function in severely ill patients.
- Other names
- UC-MSCshUC-MSCshuman umbilical cord-derived mesenchymal stem cells
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