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human umbilical cord-derived mesenchymal stem cells (Shandong University)

Development stage: Unknown
Lead developer: Shandong University
Modality: Stem Cell Therapies → Cell Therapies
Administration: Intravenous

Overview

This investigational cell therapy, developed by Shandong University, utilizes human umbilical cord-derived mesenchymal stem cells (UC-MSCs) for the treatment of type 2 diabetes mellitus. UC-MSCs are adult stem cells characterized by their potent anti-inflammatory and immunomodulatory properties. The therapy is administered via intravenous infusion and is designed to improve islet β-cell function and decrease systemic insulin resistance. Clinical evaluation in a Phase 2 trial (NCT02302599) demonstrated that a significant proportion of patients achieved improved glycemic control (HbA1c < 7.0%) and a reduction in daily insulin requirements following treatment.

Other names: UC-MSCshuman umbilical cord/placenta-derived mesenchymal stem cells

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