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human umbilical cord mesenchymal stem cell-derived small extracellular vesicles
- Development stage
- Unknown
- Lead developer
- Shenzhen People's Hospital
- Modality
- Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Cell Therapies
- Administration
- Intradermal
01
Overview
Human umbilical cord mesenchymal stem cell-derived small extracellular vesicles (hUCMSC-sEV) are nanoscale vesicles (exosomes) secreted by mesenchymal stem cells harvested from the umbilical cord. Developed by Shenzhen People's Hospital, these vesicles function as natural intercellular communication vehicles that transport a cargo of proteins, microRNAs (miRNAs), and other bioactive molecules to recipient cells. In the treatment of androgenetic alopecia, hUCMSC-sEVs are intended to promote tissue repair, mitigate inflammation, and stimulate hair follicle regeneration. The therapy is currently being evaluated in a Phase 1/2 clinical trial to assess its safety and efficacy compared to topical minoxidil in young men with hair loss.
- Other names
- human umbilical cord mesenchymal stem cell exosomeshUCMSC exosomes
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