Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
human umbilical cord mesenchymal stem cell secretome
- Development stage
- Phase 4
- Lead developer
- Universitas Indonesia
- Modality
- Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Intravenous
01
Overview
Human umbilical cord mesenchymal stem cell (HUCMSC) secretome is a cell-free therapeutic product derived from the conditioned media of mesenchymal stem cells harvested from human umbilical cord tissue. It comprises a complex cocktail of bioactive paracrine factors, including cytokines, chemokines, growth factors, and extracellular vesicles (such as exosomes). The secretome acts as an immunomodulatory and neuroprotective agent by modulating the inflammatory microenvironment—specifically reducing pro-inflammatory cytokines like IL-6 and TNF-alpha—and providing trophic support for tissue regeneration. As a cell-free alternative to live stem cell therapy, it offers advantages in safety, standardization, and reduced risk of immunogenicity or tumorigenicity. It is currently being investigated in clinical trials for neurological conditions, including moderate dementia and drug-resistant epilepsy.
- Brand names
- Regenic
- Other names
- human umbilical cord mesenchymal stem cell-derived secretomeumbilical cord MSC secretomeMSC secretome
02
Targets
IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))
Beyond the preview
Go deeper on human umbilical cord mesenchymal stem cell secretome.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on human umbilical cord mesenchymal stem cell secretome.