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human umbilical cord mesenchymal stem cells (Evive Biotechnology)
- Development stage
- Unknown
- Lead developer
- Hangzhou Yi Wen Race Biotechnology
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
Human umbilical cord mesenchymal stem cells are an investigational **allogeneic stem cell therapy** composed of mesenchymal stromal cells isolated from healthy newborn umbilical cord tissue, screened, and expanded ex vivo for clinical use. In the context provided, the product is being developed by **Hangzhou Yivensai Biotechnology** as a **human umbilical cord mesenchymal stem cell injection** for **moderate to severe acute respiratory distress syndrome**. Its proposed mechanism is primarily **immunomodulatory and paracrine** rather than target-selective receptor pharmacology: the administered cells are intended to dampen dysregulated pulmonary inflammation, including suppression of inflammatory macrophage responses, secretion of soluble mediators such as prostaglandin E2, and broader modulation of immune-cell activity in the injured lung microenvironment. The cited program has no publicly identified brand name and is in clinical development following reported IND clearance in China.
- Other names
- human umbilical cord mesenchymal stem cellshuman umbilical cord mesenchymal stem cellhuman umbilical cord mesenchymal stem cell injectionhUC-MSCsumbilical cord mesenchymal stem cells
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