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human umbilical cord mesenchymal stem cells (Renmin Hospital of Wuhan University)
- Development stage
- Unknown
- Lead developer
- Renmin Hospital of Wuhan University
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intravenous
01
Overview
This investigational cell therapy consists of human umbilical cord-derived mesenchymal stem cells (UC-MSCs) isolated from Wharton's jelly of healthy donors. Developed by Renmin Hospital of Wuhan University, it is being evaluated for the treatment of diabetic nephropathy in patients with type 2 diabetes. The therapy is administered via peripheral intravenous infusion and exerts its therapeutic effects through multiple mechanisms, including anti-inflammatory, anti-fibrotic, and immunomodulatory actions. By targeting renal inflammation, fibrosis, and epithelial-mesenchymal transition, the UC-MSCs aim to preserve renal function and reduce proteinuria in patients with chronic kidney damage resulting from diabetes.
- Other names
- hUC-MSCsumbilical cord-derived mesenchymal stem cellshuman umbilical cord-derived mesenchymal stem cells
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