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human umbilical cord mesenchymal stem cells + neural stem cells
- Development stage
- Unknown
- Lead developer
- Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intrathecal, Intravenous, Intralesional
01
Overview
Human umbilical cord mesenchymal stem cells (hUCMSCs) combined with neural stem cells (NSCs) is an experimental combination cell therapy being investigated for the treatment of neurodegenerative diseases, primarily Amyotrophic Lateral Sclerosis (ALS). The therapy leverages the synergistic potential of two distinct stem cell populations: hUCMSCs, which are known for their potent immunomodulatory and anti-inflammatory properties, and NSCs, which possess the ability to differentiate into neural cells and provide direct neurotrophic support to motor neurons. By administering these cells, typically through intrathecal or intravenous routes, the treatment aims to slow disease progression by mitigating neuroinflammation, preventing motor neuron apoptosis, and potentially promoting neural repair. The development of this combination is currently being explored in early-phase clinical trials by institutions such as the Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine.
- Other names
- hUCMSC+NSC therapyhUCMSC+NSChuman umbilical cord mesenchymal stem cells combined with neural stem cells
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