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Humylub Ofteno PF
- Development stage
- Phase 4
- Lead developer
- Laboratorios Sophia
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
**Humylub Ofteno PF** is an ophthalmic solution containing **sodium hyaluronate 0.1%** and **chondroitin sulfate 0.18%**, developed by **Laboratorios Sophia** for the treatment of mild to moderate **dry eye disease**. It functions as a lubricant by mimicking natural tears, with sodium hyaluronate providing viscoelastic hydration to the ocular surface and chondroitin sulfate enhancing mucoadhesion and protection against epithelial damage. The product is preservative-free (PF), suitable for frequent use, and has demonstrated efficacy in improving symptoms (OSDI score), tear break-up time, ocular staining, and hyperemia in a completed Phase 4 non-inferiority trial against comparators like Hyabak and Lagricel Ofteno PF.[1][3][8][10]
- Brand names
- Humylub Ofteno PF
- Other names
- chondroitin sulfate + sodium hyaluronate
02
Targets
CD44 (CD44 antigen)ICAM1 (Intercellular Adhesion Molecule 1)RHAMM (Hyaluronan-mediated motility receptor)HMMR
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