Drug intelligence / Profile preview

Humylub Ofteno PF

Development stage
Phase 4
Lead developer
Laboratorios Sophia
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

**Humylub Ofteno PF** is an ophthalmic solution containing **sodium hyaluronate 0.1%** and **chondroitin sulfate 0.18%**, developed by **Laboratorios Sophia** for the treatment of mild to moderate **dry eye disease**. It functions as a lubricant by mimicking natural tears, with sodium hyaluronate providing viscoelastic hydration to the ocular surface and chondroitin sulfate enhancing mucoadhesion and protection against epithelial damage. The product is preservative-free (PF), suitable for frequent use, and has demonstrated efficacy in improving symptoms (OSDI score), tear break-up time, ocular staining, and hyperemia in a completed Phase 4 non-inferiority trial against comparators like Hyabak and Lagricel Ofteno PF.[1][3][8][10]

Brand names
Humylub Ofteno PF
Other names
chondroitin sulfate + sodium hyaluronate
02

Targets

ICAM1 (Intercellular Adhesion Molecule 1)RHAMM (Hyaluronan-mediated motility receptor)CD44 (CD44 antigen)

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