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huo xue chang zhi
- Development stage
- Unknown
- Lead developer
- Xuanwu Hospital
- Administration
- Oral
01
Overview
Huo Xue Chang Zhi is a Traditional Chinese Medicine (TCM) herbal formulation, typically administered as granules, specifically developed for the treatment of post-stroke depression (PSD). The formula is designed based on the TCM principles of "invigorating blood to remove stasis" (Huo Xue) and "soothing the liver to relieve depression" (Chang Zhi), addressing the dual pathology of blood stasis and Qi stagnation common in stroke survivors. Clinical research, primarily led by institutions in China, suggests that the formula may improve depressive symptoms and neurological recovery by modulating monoamine neurotransmitters and increasing the expression of neurotrophic factors. It is often studied as an alternative or adjunctive therapy to conventional antidepressants like SSRIs.
- Brand names
- Huo Xue Chang Zhi
- Other names
- 活血畅志Huo Xue Chang Zhi FangHuo Xue Chang Zhi GranulesHXG
02
Targets
5-HT (Serotonin receptors)BDNF (Brain-derived neurotrophic factor)
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