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huoxia ganmao keli
- Development stage
- Phase 3
- Lead developer
- Yiling Pharmaceutical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Huoxia Ganmao Keli (藿夏感冒颗粒) is a 1.1-class innovative traditional Chinese medicine (TCM) developed by Yiling Pharmaceutical. It is a multi-herb granule formulation designed to treat the common cold and gastrointestinal cold (characterized by the TCM syndrome pattern of wind-pathogen attacking the exterior with dampness obstructing the middle). The formulation works by releasing the exterior, harmonizing the middle, expelling filth, and resolving dampness. It is currently in Phase III clinical development in China.
- Other names
- Huoxia Ganmao granulesHuoxia Ganmao Keli藿夏感冒颗粒
02
Targets
DPP-4 (Dipeptidyl Peptidase-IV)EGFR (Epidermal growth factor receptor)IKBKB (IKKβ)IL-6R (Interleukin-6 receptor subunit alpha)MAPK14 (p38 mitogen-activated protein kinase alpha)MAPK3 (Mitogen-activated protein kinase 1)JNK (Mitogen-activated protein kinase kinase kinase family)RELA (Nuclear Factor Kappa B Subunit p65)STAT3 (Signal Transducer and Activator of Transcription 3)
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