Drug intelligence / Profile preview

Huoxiang Zhengqi Granules

Development stage
Unknown
Lead developer
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
Administration
Oral
01

Overview

Huoxiang Zhengqi Granules is a traditional Chinese patent medicine (CPM) formulation used to treat gastrointestinal disorders, particularly those characterized by 'dampness' and 'summer-heat' in Traditional Chinese Medicine (TCM). The formula is a complex mixture of herbs, typically including *Agastache rugosa*, *Atractylodes lancea*, *Citrus reticulata*, *Magnolia officinalis*, *Platycodon grandiflorus*, *Poria cocos*, and *Glycyrrhiza uralensis*. It is commonly indicated for gastrointestinal flu, heatstroke, and acute gastritis. During the COVID-19 pandemic, Huoxiang Zhengqi Granules was included in Chinese national treatment guidelines and evaluated in clinical registry studies (such as ChiCTR2200059413) for the management of mild COVID-19 symptoms, focusing on its potential to improve recovery rates and viral clearance.

Brand names
Huoxiang Zhengqi
Other names
Huoxiang Zhengqi Keli藿香正气颗粒
02

Targets

MAPK14 (p38 mitogen-activated protein kinase alpha)MAPK3 (Mitogen-activated protein kinase 1)JNK (Mitogen-activated protein kinase kinase kinase family)PGHS-1 (Prostaglandin G/H Synthase 1)STAT3 (Signal Transducer and Activator of Transcription 3)

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