Drug intelligence / Profile preview

huoxiang zhengqi oral liquid

Development stage
Unknown
Lead developer
Taiji Group
Modality
Small Molecules
Administration
Oral
01

Overview

Huoxiang Zhengqi Oral Liquid is a classic Chinese patent medicine used for more than 1,000 years to treat gastrointestinal and respiratory diseases. It is composed of multiple herbal ingredients including patchouli oil (Agastache), perilla leaf oil, Poria cocos, Angelica dahurica root, Atractylodes macrocephala rhizome, Magnolia officinalis bark (processed with ginger), tangerine peel (Citrus reticulata pericarp), Pinellia ternata tuber, licorice extract (Glycyrrhiza glabra root and rhizome), Areca catechu peel[1][5][7]. The product is indicated for relieving external symptoms and resolving dampness; regulating qi and harmonizing the central nervous system. It is used for colds caused by exogenous wind-cold or internal damage due to dampness or summer-heat dampness. Symptoms include headache, dizziness, chest tightness, epigastric/abdominal distension/pain, vomiting/diarrhea; also for gastrointestinal colds with these symptoms[1][7]. Recent studies suggest it may have anti-inflammatory effects by modulating short-chain fatty acid levels and inhibiting the TLR4/NF-κB pathway[8][9].

Brand names
Tai Chi-Huoxiang Zhengqi Oral LiquidOyama Line Huoxiang Zhengqi Oral Liquid
Other names
藿香正气口服液Huo Xiang Zheng Qi ShuiAgastache Tummy Syrup (in some contexts)Huo Xiang Zheng Qi Gao (in some contexts)
02

Targets

NF-κBMYD88 (Myeloid differentiation primary response protein MyD88)CD14 (Monocyte differentiation antigen CD14)TLR4 (Toll-like receptor 4)

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