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Huoxiang Zhengqi Powder is a classic traditional Chinese medicine (TCM) herbal formula used primarily to treat disorders associated with "dampness" and "wind-cold" according to TCM theory. It is widely prescribed for acute gastroenteritis (vomiting, diarrhea, abdominal pain), summer colds (chills, fever), heat stroke (dizziness, nausea), stomach cold/discomfort and related gastrointestinal disturbances. The formula contains multiple herbs including Agastache rugosa (patchouli), Perilla leaf, Angelica dahurica root, Pinellia ternata rhizome, Magnolia officinalis bark, tangerine peel (Citrus reticulata), Areca husk (Da Fu Pi), Platycodon grandiflorum root (Jie Geng), Atractylodes macrocephala rhizome (Bai Zhu), Poria cocos sclerotium (Fu Ling), Glycyrrhiza uralensis root/prepared licorice root and others[6][8][10]. Modern pharmacological studies indicate the formula has antibacterial, antiviral, antipyretic/antipyretic-like effects; it regulates gastrointestinal function and protects intestinal mucosa[1][3][6]. Mechanistically it exhibits anti-inflammatory activity by modulating cytokines such as TNF-α and IL-6; active ingredients like quercetin and luteolin interact with targets including EGFR and MAPK pathways[5]. It is available in various forms such as powders ("san"), pills ("wan"), granules or oral liquids.
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