Drug intelligence / Profile preview

huoxiang zhengqi powder

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Huoxiang Zhengqi Powder is a classic traditional Chinese medicine (TCM) herbal formula used primarily to treat disorders associated with "dampness" and "wind-cold" according to TCM theory. It is widely prescribed for acute gastroenteritis (vomiting, diarrhea, abdominal pain), summer colds (chills, fever), heat stroke (dizziness, nausea), stomach cold/discomfort and related gastrointestinal disturbances. The formula contains multiple herbs including Agastache rugosa (patchouli), Perilla leaf, Angelica dahurica root, Pinellia ternata rhizome, Magnolia officinalis bark, tangerine peel (Citrus reticulata), Areca husk (Da Fu Pi), Platycodon grandiflorum root (Jie Geng), Atractylodes macrocephala rhizome (Bai Zhu), Poria cocos sclerotium (Fu Ling), Glycyrrhiza uralensis root/prepared licorice root and others[6][8][10]. Modern pharmacological studies indicate the formula has antibacterial, antiviral, antipyretic/antipyretic-like effects; it regulates gastrointestinal function and protects intestinal mucosa[1][3][6]. Mechanistically it exhibits anti-inflammatory activity by modulating cytokines such as TNF-α and IL-6; active ingredients like quercetin and luteolin interact with targets including EGFR and MAPK pathways[5]. It is available in various forms such as powders ("san"), pills ("wan"), granules or oral liquids.

Brand names
Patchouli Qi Rectifying Powder
Other names
Agastachis Powder for Restoring Vital QiHuoxiang Zhengqi SanHuo Xiang Zheng Qi Granules
02

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)IL-6 (Interleukin 6)JNK (Mitogen-activated protein kinase kinase kinase family)TNFA (Tumor necrosis factor alpha (soluble))EGFR T790M (Epidermal growth factor receptor T790M mutant)MAPK3 (Mitogen-activated protein kinase 1)

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