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Huoxue Bushen Anshen prescription
- Development stage
- Unknown
- Lead developer
- Guang'anmen Hospital
- Administration
- Oral
01
Overview
Huoxue Bushen Anshen prescription is a traditional Chinese medicine (TCM) formulation developed by Guang'anmen Hospital, China Academy of Chinese Medical Sciences. It is designed as an add-on therapy to standard-of-care treatments for patients with chronic heart failure secondary to acute myocardial infarction. The formulation specifically targets the TCM syndrome characterized by Qi deficiency, blood stasis, and kidney deficiency. Its therapeutic rationale is based on the TCM principles of 'Huoxue' (promoting blood circulation and removing stasis), 'Bushen' (tonifying the kidney), and 'Anshen' (calming the mind and tranquilizing). By addressing these underlying imbalances, the prescription aims to improve cardiac function, alleviate clinical symptoms, and enhance the quality of life in adult patients. It is currently being evaluated in a Phase 3 randomized, placebo-controlled clinical trial in China.
- Other names
- Huoxue Bushen Anshen decoctionHuoxue Bushen Anshen formula
02
Targets
FOXO1 (Forkhead box protein O1)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)FABP1 (Fatty acid-binding protein 1)HIF-1α (Hypoxia-inducible factor 1-alpha)
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