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Huoyang Zhitong Ointment
- Development stage
- Phase 2
- Lead developer
- Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Huoyang Zhitong Ointment is a traditional Chinese medicine (TCM) topical preparation developed by the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University. Classified as a hospital-made preparation (院内制剂) in China, it is primarily indicated for the treatment of knee osteoarthritis and synovitis. The formulation is designed to warm the meridians and dispel cold and pain, aligning with TCM principles for treating joint disorders characterized by blood stasis and dampness. It works by modulating local inflammatory responses, specifically inhibiting mediators like COX-2 and pro-inflammatory cytokines, thereby reducing joint pain, swelling, and stiffness. It is a staple therapeutic in the hospital's orthopedic department for managing chronic inflammatory joint conditions.
- Brand names
- Huoyang Zhitong Ointment
- Other names
- 火阳止痛膏Huo Yang Zhi Tong Gao
02
Targets
IL1B (Interleukin-1 beta)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TNFA (Tumor necrosis factor alpha (soluble))
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