Drug intelligence / Profile preview

Huoyang Zhitong Ointment

Development stage
Unknown
Lead developer
Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University
Modality
Small Molecules
Administration
Topical
01

Overview

Huoyang Zhitong Ointment is a traditional Chinese medicine (TCM) topical preparation developed by the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University. Classified as a hospital-made preparation (院内制剂) in China, it is primarily indicated for the treatment of knee osteoarthritis and synovitis. The formulation is designed to warm the meridians and dispel cold and pain, aligning with TCM principles for treating joint disorders characterized by blood stasis and dampness. It works by modulating local inflammatory responses, specifically inhibiting mediators like COX-2 and pro-inflammatory cytokines, thereby reducing joint pain, swelling, and stiffness. It is a staple therapeutic in the hospital's orthopedic department for managing chronic inflammatory joint conditions.

Brand names
Huoyang Zhitong Ointment
Other names
火阳止痛膏Huo Yang Zhi Tong Gao
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))PTGS2 (Prostaglandin-Endoperoxide Synthase 2)IL1B (Interleukin-1 beta)

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