HY-072808

HY-072808 is a novel small molecule phosphodiesterase 4 (PDE4) inhibitor developed for topical treatment of mild to moderate atopic dermatitis. It acts by inhibiting PDE4, an enzyme involved in the inflammatory response, thereby reducing inflammation and pruritus associated with atopic dermatitis. The drug is formulated as an ointment and has demonstrated favorable safety, pharmacokinetics, and efficacy profiles in clinical studies involving both healthy subjects and patients with atopic dermatitis. After topical administration, systemic exposure is low, supporting its use for localized skin conditions[1][2][4][5][7][8].

Other names

HY072808HY-072808HY 072808