Drug intelligence / Profile preview

HY-111996

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

HY-111996 is a small molecule drug candidate that acts as a modulator of Kv3 voltage-gated potassium channels. It is referenced in the literature as "Kv3 modulator 1" and has been investigated for its effects on central nervous system disorders, particularly schizophrenia. The compound's mechanism involves modulation of the Kv3 family of potassium channels, which are important for regulating neuronal excitability and fast-spiking interneuron function. Clinical trials have evaluated its safety, tolerability, and pharmacokinetics in patients with schizophrenia[2][7][3].

Other names
Kv3 modulator 1Kv-3 modulator 1Kv 3 modulator 1Compound X (from patent WO2018020263A1)
02

Targets

KCNC4 (Potassium voltage-gated channel subfamily C member 4)

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