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Hy-ter
- Development stage
- Phase 4
- Lead developer
- NTC Pharma
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Topical
01
Overview
Hy-ter is a topical medical device formulated as pre-moistened lid wipes for the treatment of seborrheic blepharitis and the management of eyelid hygiene. The product contains two primary active ingredients: terpinen-4-ol, the main constituent of tea tree oil, and sodium hyaluronate. Terpinen-4-ol provides antimicrobial, anti-inflammatory, and acaricidal properties, specifically targeting *Demodex* mites which are frequently associated with blepharitis. Sodium hyaluronate acts as a moisturizing and lubricating agent to soothe the eyelid skin and maintain the integrity of the tear film. Hy-ter was evaluated in a randomized, double-blind Phase 4 clinical trial conducted by researchers at Istanbul University - Cerrahpasa, where it demonstrated significant efficacy in reducing symptoms and *Demodex* counts compared to standard treatments like baby shampoo. It is manufactured by NTC (Novelty Technology Care) in Italy.
- Brand names
- Hy-terBlefastop
- Other names
- terpinen-4-ol + sodium hyaluronate lid wipes
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