Drug intelligence / Profile preview

HY3003

Development stage
Preclinical
Lead developer
Hybio Pharmaceutical
Modality
Peptides
Administration
Subcutaneous, Oral
01

Overview

HY3003 is a triple agonist peptide innovative drug being developed by Hybio Pharmaceuticals in collaboration with iCarbonX. It targets the glucagon-like peptide-1 receptor (GLP-1R), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon receptor (GCGR) to provide multi-hormonal metabolic effects for the treatment of obesity, type 2 diabetes, and other metabolic diseases. Discovered using AI-integrated peptide chip technology, the drug is currently in preclinical development. The development program includes a monthly subcutaneous long-acting sustained-release injectable formulation and an oral formulation.

02

Targets

GIPR (Gastric inhibitory polypeptide receptor)GLP1R (GLP-1R)GCGR (Glucagon receptor)

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