Drug intelligence / Profile preview

Hy5 Duo

Development stage
Unknown
Lead developer
Optho Pharma
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Hy5 Duo is a dual-action lubricant eye drop developed and marketed by Optho Pharma for the treatment of dry eye syndrome and associated ocular irritation. It is a fixed-dose combination of sodium carboxymethylcellulose (1% w/v) and sodium hyaluronate (0.1% w/v). Sodium hyaluronate is a naturally occurring biopolymer with high water-binding capacity that acts as an effective lubricant, spreading evenly across the cornea to reduce friction and promote healing. Sodium carboxymethylcellulose is a viscosity-enhancing polymer that prolongs the residence time of the drops on the ocular surface, providing long-lasting moisture and protection. Together, these components mimic natural tears to soothe burning, itching, and grittiness caused by environmental factors or post-operative recovery.

Brand names
Hy5 DuoHy-5 DuoHy 5 Duo
Other names
sodium carboxymethylcellulose + sodium hyaluronatesodium hyaluronate + sodium carboxymethylcellulose
02

Targets

CD44 (CD44 antigen)GLUT1 (Glucose transporter 1)

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