Hyalgen

**Hyalgen** is a topical nanoparticle-based dermatology and aesthetic skin care serum developed by **Endor Nanotechnology** for professional use as an adjuvant to facial aesthetic procedures. The product is described as containing **Gold Thioethylamino Hyaluronic Acid** consisting of low molecular weight hyaluronic acid-coated gold nanoparticles, with reported particle dimensions of about 10 nm gold cores and roughly 22 nm final particles. Its proposed mechanism is targeted interaction of the hyaluronic acid-coated nanoparticles with **CD44**, with downstream stimulation of endogenous hyaluronic acid, collagen, and elastin production to improve skin firmness and reduce fine lines and wrinkles. Hyalgen appears to have been positioned as a cosmeceutical or dermatology product used topically in combination with radiofrequency and other aesthetic procedures such as HIFU, microneedling, and plasma pen treatments rather than as a conventional approved pharmaceutical therapeutic.

Brand names

Hyalgen

Other names

Gold Thioethylamino Hyaluronic AcidAuHA