Drug intelligence / Profile preview

Hyalodisc

Development stage
Unknown
Lead developer
Johnson & Johnson
Modality
Small Molecules
Administration
Intradiscal
01

Overview

**Hyalodisc** is a hyaluronic acid-based intradiscal injection formulation (8 mg/mL) designed for X-ray-guided administration into the intervertebral disc. It acts as a viscosupplement, mimicking the viscoelastic properties of natural hyaluronic acid in synovial fluid to provide lubrication, shock absorption, and structural support within the disc, potentially alleviating pain associated with degenerative disc disease. Evaluated in clinical investigation NCT04757038, it is combined with PEP (positioning and exercise program) to assess efficacy in disc-related back pain, targeting patients unresponsive to conservative therapies.[6]

Brand names
Hyalodisc
02

Targets

HMMRCD44 (CD44 antigen)

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