Drug intelligence / Profile preview

hyaluronic acid + calcium hydroxyapatite

Development stage
Unknown
Lead developer
Allergan Aesthetics
Administration
Intradermal
01

Overview

Hyaluronic acid + calcium hydroxyapatite is a hybrid dermal filler that combines the immediate volumizing effects of cross-linked hyaluronic acid with the long-term biostimulatory properties of calcium hydroxyapatite microspheres. Developed by Allergan Aesthetics (an AbbVie company) under the brand name HArmonyCa (originally developed by Luminera), this injectable formulation is designed for facial soft tissue augmentation, particularly in the mid and lower face. The hyaluronic acid component provides instant lift and volume through mechanical support, while the calcium hydroxyapatite microspheres stimulate fibroblasts to promote neocollagenesis, leading to sustained improvements in skin quality and structural integrity. A version containing lidocaine (HArmonyCa-L) is also available to improve patient comfort during the procedure.

Brand names
HArmonyCaHArmonyCa-LRveiling HA-CaHA
Other names
HA-CaHA fillerhyaluronic acid and calcium hydroxyapatite hybrid filler

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