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hyaluronic acid + alpha-lipoic acid + magnesium + vitamin D + vitamin B6
- Development stage
- Unknown
- Lead developer
- Lo.Li. Pharma
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
DAV-HA is an oral nutritional supplement combination developed by LoLi Pharma srl. It is composed of high-molecular-weight hyaluronic acid (HMWHA), alpha-lipoic acid (ALA), magnesium, vitamin B6, and vitamin D. The product is specifically formulated for use in pregnant women to manage complications such as threatened miscarriage and subchorionic hematoma. Its mechanism involves the anti-inflammatory and antioxidant properties of alpha-lipoic acid and hyaluronic acid, the tocolytic effects of magnesium in reducing uterine contractions, and the immunomodulatory roles of vitamins D and B6. Clinical pilot studies have indicated that DAV-HA supplementation can improve the resorption of subchorionic hematomas and reduce the incidence of preterm birth and related hospitalizations.
- Brand names
- DAV-HA
- Other names
- DAV-HAhyaluronic acid + alpha-lipoic acid + magnesium + vitamin B6 + vitamin D
02
Targets
VDR (Vitamin D receptor)
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