Drug intelligence / Profile preview

hyaluronic acid + arginine

Development stage
Phase 3
Lead developer
Dermofarm
Modality
Small Molecules
Administration
Topical, Vaginal
01

Overview

Hyaluronic acid + arginine is a combination formulation utilized in pharmaceutical and medical device applications for its synergistic effects on tissue hydration, microcirculation, and structural repair. Hyaluronic acid (HA), a major glycosaminoglycan of the extracellular matrix, functions as a high-capacity humectant and viscoelastic agent that promotes cell migration and proliferation by binding to receptors such as CD44. Arginine, a semi-essential amino acid, serves as the primary biological precursor for nitric oxide (NO) production via the action of nitric oxide synthases (NOS). The localized release of nitric oxide enhances microvascular blood flow, modulates inflammatory responses, and stimulates fibroblast activity, thereby increasing collagen and elastin synthesis. This combination is specifically developed for the treatment of Genitourinary Syndrome of Menopause (GSM) and atrophic vaginitis to restore mucosal integrity, as well as in topical applications for wound healing, radiotherapy-induced burns, and aesthetic intimate rejuvenation.

Brand names
Viderage
Other names
arginine hyaluronateHA-ArginineHA+Arghyaluronan + L-arginine
02

Targets

CD44 (CD44 antigen)RHAMM (Hyaluronan-mediated motility receptor)NOS2 (Nitric Oxide Synthase 2)

Beyond the preview

Go deeper on hyaluronic acid + arginine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on hyaluronic acid + arginine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call