hyaluronic acid + ketorolac

hyaluronic acid + ketorolac is a combination therapy investigated by Mahidol University for the treatment of adhesive capsulitis (frozen shoulder). The treatment involves a single intra-articular injection containing moderate-molecular-weight hyaluronic acid, which provides mechanical lubrication (viscosupplementation) and biological signaling through CD44 receptors, and ketorolac, a non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes to reduce local inflammation and pain. In clinical trials, the formulation often included lidocaine as a local anesthetic. This combination aims to improve shoulder function and range of motion more effectively than anti-inflammatory treatment alone by addressing both the inflammatory and mechanical components of the disease.

Other names

Intra-articular Hyaluronic Acid and KetorolacHA + ketorolac