hyaluronic acid + lidocaine (AbbVie Inc.)

VYC-12L, marketed as Juvéderm Volite, is an injectable dermal filler developed by Allergan (now part of AbbVie) using proprietary Vycross technology. It consists of a crosslinked hyaluronic acid (HA) hydrogel at a concentration of 12 mg/mL, formulated with 0.3% lidocaine to minimize injection-site discomfort. Unlike traditional fillers designed for volume restoration, VYC-12L is specifically engineered for intradermal injection to improve skin quality attributes such as hydration, elasticity, and smoothness, and to correct superficial fine lines. The Vycross technology utilizes a combination of low- and high-molecular-weight HA to create a tightly crosslinked network, which enhances the gel's duration of effect—typically lasting up to nine months after a single treatment—while maintaining a smooth consistency for natural-looking results.

Brand names

Juvéderm VoliteVolite

Other names

crosslinked hyaluronic acid with lidocaine