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hyaluronic acid + recombinant collagen
- Development stage
- Unknown
- Lead developer
- Fujifilm
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Recombinant Proteins and Enzymes, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Intradermal, Subcutaneous, Topical
01
Overview
The combination of hyaluronic acid and recombinant collagen represents a synergistic approach in regenerative medicine and medical aesthetics. Hyaluronic acid (HA), a naturally occurring glycosaminoglycan, provides immediate physical volumization and hydration due to its high water-binding capacity. Recombinant collagen, typically produced using recombinant DNA technology in plant (e.g., tobacco) or yeast systems, offers a biomimetic scaffold that closely mimics the human extracellular matrix. Unlike animal-derived collagen, recombinant human collagen (rhCollagen) minimizes immunogenic risks and provides a consistent, high-purity substrate for cellular attachment and tissue integration. This combination is primarily utilized as a next-generation dermal filler to stimulate endogenous collagen production and as a bioactive dressing for wound healing and tendon repair.
- Brand names
- VergenixMicoreColChuangfuCol-HA
- Other names
- rhCollagen-HA fillerrecombinant humanized collagen type III + hyaluronic acidbiomimetic filler
02
Targets
CD44 (CD44 antigen)Integrin (Integrin family)ITGA2 (Integrin alpha-2)
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