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hyaluronic acid sodium salt
- Development stage
- Phase 4
- Lead developer
- Seikagaku
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Intraarticular, Ophthalmic, Topical, Subcutaneous, Intradermal, Intranasal
01
Overview
Hyaluronic acid sodium salt (commonly known as sodium hyaluronate) is the sodium salt form of hyaluronic acid, a naturally occurring glycosaminoglycan widely present in human connective, epithelial, and neural tissues. It acts as an effective tissue lubricant, wound healing promoter, and viscoelastic agent due to its ability to retain water and modulate cell signaling. It is used extensively in medicine for osteoarthritis (intra-articular injection), ophthalmology (maintenance of corneal shape and as an adjuvant in cataract/glaucoma surgery), dermatology (dermal fillers, wound healing, moisture retention in topicals), and as a component in various moisturizing and anti-aging products. The mechanism relates to its biophysical and biochemical roles as a lubricant, shock absorber, and modulator of inflammatory and cellular repair responses[1][2][3][4][6].
- Brand names
- Sodium hyaluronateHyalganOstenilHealonViscornealViscAid
- Other names
- hyaluronate sodiumsodium hyaluronatehyaluronan sodium saltHA sodium salt
02
Targets
ICAM1 (Intercellular Adhesion Molecule 1)CD44 (CD44 antigen)
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