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hyaluronidase (Esteve)
- Development stage
- Approved
- Lead developer
- Esteve
- Modality
- Therapeutic Enzymes → Recombinant Proteins and Enzymes
- Administration
- Subcutaneous, Intradermal, Intramuscular
01
Overview
Hylase Dessau is an injectable enzyme preparation containing bovine testicular hyaluronidase. It acts by depolymerizing hyaluronic acid, a major polysaccharide of the extracellular matrix, thereby decreasing the viscosity of the interstitial tissue and increasing its permeability. This spreading factor effect facilitates the diffusion and absorption of co-administered fluids and drugs. Developed by RIEMSER Pharma, it is primarily indicated as an adjuvant to enhance the spread and efficacy of local anesthetics. It is also widely used off-label in aesthetic medicine to dissolve hyaluronic acid-based dermal fillers and manage associated complications like vascular occlusion or edema.
- Brand names
- Hylase DessauHylase
- Other names
- bovine testicular hyaluronidase
02
Targets
C6S (Chondroitin-6-sulfate)
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