Drug intelligence / Profile preview

Hybridopa

Development stage
Unknown
Lead developer
Remepy
Modality
Small Molecules
Administration
Oral
01

Overview

Hybridopa is a novel hybrid therapeutic developed by Remepy that combines a levodopa-based small molecule with a digital therapeutic protocol (Software as a Medical Device). It is specifically designed for the treatment of Parkinson's Disease, targeting both motor symptoms like rigidity and non-motor symptoms such as cognitive decline. The pharmacological component, levodopa, acts as a dopamine precursor that is converted into dopamine in the central nervous system to restore neurotransmitter levels. The integrated digital therapeutic component is designed to optimize treatment outcomes and manage symptoms through autonomic regulation or behavioral interventions. The program has completed Phase 2 clinical trials and is scheduled to enter Phase 3 in late 2026.

Brand names
Hybridopa
Other names
Hybridopa™
02

Targets

DRD (Dopamine receptors)

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