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Hydralief
- Development stage
- Unknown
- Lead developer
- Entod Pharmaceuticals
- Modality
- Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
- Administration
- Ophthalmic
01
Overview
Hydralief is a sterile ophthalmic solution containing sodium hyaluronate, primarily indicated for the relief of dry eye symptoms and ocular surface irritation. Sodium hyaluronate is a high-molecular-weight polysaccharide that occurs naturally in the human eye and connective tissues, possessing significant viscoelastic and mucoadhesive properties. When applied topically, it forms a stable, long-lasting lubricating film over the corneal and conjunctival epithelium, which stabilizes the tear film and reduces evaporation. This physical barrier minimizes friction during blinking and protects the ocular surface from environmental stressors, thereby alleviating discomfort such as burning, itching, and foreign body sensation. It is commonly developed and marketed by Entod Pharmaceuticals.
- Brand names
- Hydralief
- Other names
- sodium hyaluronate eye drops
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