Drug intelligence / Profile preview

hydrocodone bitartrate + chlorpheniramine maleate

Development stage
Unknown
Lead developer
Kramer Novis
Modality
Small Molecules
Administration
Oral
01

Overview

Tusicof is a prescription combination pharmaceutical product developed by Kramer Novis, containing hydrocodone bitartrate and chlorpheniramine maleate. Hydrocodone bitartrate is an opioid antitussive that suppresses the cough reflex by acting directly on the cough center in the medulla of the brain. Chlorpheniramine maleate is a first-generation alkylamine antihistamine that provides relief from symptoms such as sneezing, rhinorrhea, and lacrimation by competitively antagonizing H1 histamine receptors. Tusicof is indicated for the symptomatic relief of cough and upper respiratory symptoms associated with the common cold or allergic rhinitis in adults and pediatric patients aged 6 years and older. It is formulated as an oral suspension for immediate release.

Brand names
Tusicof
Other names
Hydrocodone/Chlorpheniramine
02

Targets

MOR (Mu opioid receptor)HRH1 (Histamine H1 Receptor)

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