Drug intelligence / Profile preview

hydrocortisone acetate + lidocaine

Development stage
Unknown
Lead developer
Reyansh Remedies
Modality
Small Molecules
Administration
Rectal
01

Overview

Hydrocortisone acetate + lidocaine is a combination pharmaceutical product developed by Reyansh Remedies for rectal administration, typically in the form of a suppository. It combines the anti-inflammatory properties of hydrocortisone acetate, a synthetic corticosteroid that acts as a glucocorticoid receptor agonist, with the local anesthetic effects of lidocaine (also known as lignocaine), which inhibits voltage-gated sodium channels. This dual-action formulation is designed to provide symptomatic relief from pain, itching, and inflammation associated with anorectal conditions such as hemorrhoids, anal fissures, and proctitis. The product is approved and marketed as part of Reyansh Remedies' portfolio of generic medications.

Brand names
AnaMantle HCLida Mantle HCLidaMantle HC ReliefLidoCortPeranex HCAna-Lex
Other names
hydrocortisone acetate + lignocainelignocaine + hydrocortisone acetate
02

Targets

NaV (Voltage-gated sodium channels)GR (Glucocorticoid receptor)

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