Drug intelligence / Profile preview

hydrocortisone butyrate + mupirocin

Development stage
Unknown
Lead developer
Astellas Pharma
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Hydrocortisone butyrate + mupirocin is a topical combination therapy consisting of a synthetic corticosteroid (hydrocortisone butyrate) and an antibiotic (mupirocin). Hydrocortisone butyrate acts as an anti-inflammatory agent by binding to glucocorticoid receptors, reducing redness, itching, swelling, and other symptoms associated with inflammatory skin conditions. Mupirocin is an antibacterial agent that inhibits bacterial protein synthesis by binding to bacterial isoleucyl-tRNA synthetase, effectively stopping the growth of susceptible bacteria such as Staphylococcus aureus. This combination is used primarily for the treatment of mild to moderate atopic dermatitis or eczema in patients where secondary bacterial infection or colonization (especially with S. aureus) is suspected or confirmed. The combination has been shown to be safe and effective in infants and children for short-term use[1][3].

Other names
hydrocortisone butyrate and mupirocinhydrocortisone + mupirocin
02

Targets

GR (Glucocorticoid receptor)IleRS (Isoleucyl-tRNA synthetase)

Beyond the preview

Go deeper on hydrocortisone butyrate + mupirocin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on hydrocortisone butyrate + mupirocin.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call