Drug intelligence / Profile preview

hydrogen peroxide

Development stage
Approved
Lead developer
Abbott
Modality
Small Molecules
Administration
Topical
01

Overview

Hydrogen peroxide is a small molecule chemical compound (H2O2) widely used as an antiseptic, disinfectant, and bleaching agent. Medically, it is applied topically to prevent infection in minor cuts, scrapes, and burns and can be used as a mouth rinse for oral debridement or minor mouth irritation. It acts by releasing oxygen upon contact with tissue fluids; this foaming action helps remove debris and dead tissue from wounds. Its primary mechanism of action is the generation of free hydroxyl radicals through oxidative reactions (notably the Fenton reaction), which cause oxidative damage to proteins, membrane lipids, and DNA in microorganisms—resulting in broad-spectrum antimicrobial activity[1][2][5]. Hydrogen peroxide is also used industrially for disinfection/sterilization and as a bleaching agent[8]. It has been approved for topical use on skin lesions such as raised seborrheic keratoses[3][4].

Brand names
Peroxyl
Other names
H2O2H-2O2H 2O2perhydrol
02

Targets

PTPN1 (Protein tyrosine phosphatase 1B)

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