Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
hydromorphone (Knoll)
- Development stage
- Approved
- Lead developer
- Abbott
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Administration
- Oral, Rectal, Intravenous, Intramuscular, Subcutaneous
01
Overview
Hydromorphone is a semi-synthetic opioid analgesic derived from morphine. It is used for the management of moderate to severe acute pain and severe chronic pain in patients who require an opioid analgesic and for whom alternative treatments are inadequate. Hydromorphone acts primarily as an agonist at the mu-opioid receptor in the central nervous system, altering the perception and response to pain. It has a rapid onset of action and is approximately 2–8 times more potent than morphine. Hydromorphone can be administered orally (tablets, solution), rectally (suppositories), or parenterally (injection). Its use carries risks of respiratory depression, dependence, addiction, and withdrawal symptoms if discontinued abruptly[1][2][3][4][5][6].
- Brand names
- DilaudidDilaudid-5Dilaudid5Dilaudid 5ExalgoPalladone
- Other names
- hydromorphinedihydromorphinone
02
Targets
DOR (Opioid Receptor Delta 1)KOR (Kappa opioid receptor)MOR (Mu opioid receptor)
Beyond the preview
Go deeper on hydromorphone (Knoll).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on hydromorphone (Knoll).