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hydroquinone + mometasone furoate
- Development stage
- Unknown
- Lead developer
- Allendale Biosciences
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Hydroquinone + mometasone furoate is a topical combination therapy used for the treatment of melasma and other hyperpigmentary skin conditions. Hydroquinone is a skin-depigmenting agent that works by inhibiting the enzyme tyrosinase, which is essential for the conversion of tyrosine to melanin; this reduction in melanin production lightens the affected skin areas. Mometasone furoate is a medium-potency synthetic corticosteroid that exerts anti-inflammatory, anti-pruritic, and vasoconstrictive actions by binding to glucocorticoid receptors. In this combination, mometasone helps to mitigate the skin irritation and inflammation that can be caused by hydroquinone, while also contributing to the overall reduction of hyperpigmentation by suppressing inflammatory mediators. The product is typically formulated as a cream for direct application to hyperpigmented patches.
- Other names
- hydroquinone and mometasone furoatemometasone furoate and hydroquinone
02
Targets
TYR (Tyrosinase)FXR (Farnesoid x-activated receptor)GR (Glucocorticoid receptor)
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