hydroquinone + tretinoin + mometasone furoate

Misti Cream is a topical triple-combination therapy developed and manufactured by Karlin Pharmaceuticals. It contains hydroquinone, a skin-bleaching agent; tretinoin, a retinoid that increases skin cell turnover; and mometasone furoate, a medium-potency corticosteroid that reduces inflammation. This combination is primarily indicated for the short-term treatment of moderate-to-severe melasma of the face. Hydroquinone acts by inhibiting the enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine (DOPA) and suppressing other melanocyte metabolic processes. Tretinoin promotes the detachment of cornified cells and enhances the penetration of hydroquinone, while mometasone furoate mitigates the irritation caused by the other two components.

Brand names

Misti Cream

Other names

Misti