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Hydroxypropyl cellulose
- Development stage
- Phase 4
- Lead developer
- Bausch & Lomb
- Modality
- Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Ophthalmic, Oral
01
Overview
Hydroxypropyl cellulose is a semi-synthetic derivative of cellulose used primarily as an ophthalmic lubricant and protectant. It acts as an artificial tear to relieve dryness and irritation caused by reduced tear flow in conditions such as keratoconjunctivitis sicca (dry eye syndrome) and recurrent corneal erosions. The drug works by stabilizing and thickening the precorneal tear film, prolonging its breakup time, lubricating the ocular surface, and protecting against further irritation or injury. Hydroxypropyl cellulose is also widely used in the pharmaceutical industry as an excipient—serving roles such as tablet binder, thickener, coating agent, and film former—and in food products as a thickener or emulsion stabilizer.
- Brand names
- Lacrisert
- Other names
- cellulose, 2-hydroxypropyl etherHPC
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