hydroxypropylcellulose doxorubicin

This is a **combination drug** where **doxorubicin** (an anthracycline antineoplastic agent) is formulated together with **hydroxypropylcellulose** (a water-soluble cellulose derivative), primarily to create a **mucous-membrane-adhesive or sustained-release formulation** for localized delivery, particularly for bladder instillation or post-surgical cancer site implantation. In this combination, doxorubicin serves as the cytotoxic antitumor agent, while hydroxypropylcellulose acts as a biocompatible carrier or gel matrix that prolongs local retention of doxorubicin in the targeted tissue and enhances drug uptake by tumorous tissue. This system is designed for **localized anti-cancer therapy** to maximize tumor exposure and minimize systemic toxicity, showing potential utility for bladder cancer and in-situ cancer recurrence prevention after surgery[2][1][3].

Other names

hydroxypropylcellulose doxorubicinHPC-doxorubicin