Drug intelligence / Profile preview

hydroxyquinolone

Development stage
Phase 4
Lead developer
Sanofi
Modality
Small Molecules
Administration
Topical, Vaginal
01

Overview

Hydroxyquinolone is a **small-molecule vaginal anti-infective** used in topical gynecologic care and marketed as **Trimo-San** vaginal gel. It is formulated as an acidifying vaginal gel, commonly at **0.025%**, and is used to help maintain an acidic vaginal pH, reduce bacterial overgrowth, control odor, and provide lubrication, particularly in women using a vaginal pessary for pelvic organ support. Its effect is local rather than systemic, with antimicrobial activity attributed to inhibition of bacterial growth within the vaginal environment rather than a defined single molecular target.

Brand names
Trimo-San
Other names
hydroxyquinoline sulfate
02

Targets

TOP2A (DNA topoisomerase II)

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