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HylaCare

Development stage: Unknown
Lead developer: UT Southwestern Medical Center
Modality: Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration: Topical

Overview

HylaCare is a topical cream containing hyaluronic acid, developed by the University of Texas Southwestern Medical Center. It is being investigated for its efficacy and safety in treating acute skin changes, specifically radiation dermatitis, in patients undergoing external beam radiotherapy for breast cancer. Hyaluronic acid, its active ingredient, is a high-molecular-weight polysaccharide known for its role in wound healing, promoting collagen synthesis, endothelial cell proliferation, and fibroblast migration.

Brand names: HylaCare
Other names: HylaCareTM

Targets

ICAM1 (Intercellular Adhesion Molecule 1)RHAMM (Hyaluronan-mediated motility receptor)LYVE1 (Lymphatic vessel endothelial hyaluronic acid receptor 1)STAB2 (Stabilin-2)CD44 (CD44 antigen)

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