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HylaCare
- Development stage
- Unknown
- Lead developer
- UT Southwestern Medical Center
- Modality
- Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
- Administration
- Topical
01
Overview
HylaCare is a topical cream containing hyaluronic acid, developed by the University of Texas Southwestern Medical Center. It is being investigated for its efficacy and safety in treating acute skin changes, specifically radiation dermatitis, in patients undergoing external beam radiotherapy for breast cancer. Hyaluronic acid, its active ingredient, is a high-molecular-weight polysaccharide known for its role in wound healing, promoting collagen synthesis, endothelial cell proliferation, and fibroblast migration.
- Brand names
- HylaCare
- Other names
- HylaCareTM
02
Targets
CD44 (CD44 antigen)ICAM1 (Intercellular Adhesion Molecule 1)LYVE1 (Lymphatic vessel endothelial hyaluronic acid receptor 1)RHAMM (Hyaluronan-mediated motility receptor)STAB2 (Stabilin-2)
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