hypericum perforatum aerial extract

Hypericum perforatum aerial extract is a botanical preparation derived from the flowering tops, leaves, and stems of the St. John's Wort plant (*Hypericum perforatum* L.). It contains a complex mixture of active constituents, most notably hyperforin, hypericin, and various flavonoids like quercetin and rutin. Historically used for mild to moderate depression, its primary mechanism of action involves the non-selective inhibition of the reuptake of serotonin, norepinephrine, and dopamine. Beyond its psychiatric applications, recent research has highlighted its potential in managing hepatic oxidative stress and cytoprotection in metabolic disorders like diabetes by modulating pathways involving CYP2E1 and PARP. It is widely available as both a regulated herbal medicinal product and a dietary supplement.

Brand names

KiraPerikaMovanaJarsinFeliumSedariston

Other names

St. John's Wort extractHyperici herbaHypericum extract