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Hyptis spicigera essential oil
- Development stage
- Preclinical
- Lead developer
- Institut de Recherche en Sciences de la Santé
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
*Hyptis spicigera* essential oil is a botanical extract obtained from the leaves of *Hyptis spicigera* (commonly known as black sesame or spicigera), an aromatic plant belonging to the Lamiaceae family native to tropical Africa. The essential oil is rich in monoterpenes and sesquiterpenes, including alpha-pinene, beta-pinene, and beta-caryophyllene. It has been investigated for its insecticidal, larvicidal, and repellent properties against malaria-transmitting mosquitoes, particularly *Anopheles gambiae*. Additionally, research has demonstrated its potential in malaria transmission-blocking assays, where it significantly reduces the prevalence and density of *Plasmodium falciparum* oocysts in mosquitoes. It also exhibits antibacterial and antioxidant activities.
- Other names
- Hyptis spicigera Lam. essential oilHyptis spicigera oilessential oil of Hyptis spicigera
02
Targets
Acetylcholinesterase
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