Drug intelligence / Profile preview

I-020201

Development stage
Phase 2
Lead developer
Kuros Biosciences
Modality
Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

I-020201 is a bioactive topical therapy developed for the treatment of chronic diabetic foot ulcers. It is designed to stimulate granulation tissue formation, thereby promoting wound healing in hard-to-heal diabetic foot ulcers. The drug has been evaluated as an adjunct to standard-of-care treatments in clinical trials, specifically targeting patients with chronic diabetic foot ulcers who are at high risk for poor healing outcomes. The primary mechanism involves enhancing local tissue repair and regeneration at the site of application. Clinical studies have focused on its efficacy and safety when used alongside conventional wound care regimens[1][6][8].

Other names
TG-hook PDGF-ABPDGF-AB in fibrin sealant
02

Targets

PDGFRA (Platelet-derived growth factor receptor alpha)

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