I-123 MNI-388

I-123 MNI-388 is a radiopharmaceutical imaging agent developed by the Institute for Neurodegenerative Disorders for the detection of beta-amyloid plaques in the brain. It consists of a small molecule ligand labeled with the radioisotope Iodine-123, enabling visualization and quantification of amyloid deposition using Single Photon Emission Computed Tomography (SPECT). The agent is primarily investigated as a diagnostic biomarker for Alzheimer's disease, aiming to distinguish affected individuals from healthy controls by mapping the density and distribution of amyloid-beta protein, a key pathological marker of the disease.