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I-DEFENSE is an over-the-counter ophthalmic lubricating ointment formulated to provide long-lasting moisturization and protection of the ocular surface for patients with dry eye and related ocular surface disease. It is marketed by I-MED Pharma and is designed as a high-retention, viscous eye ointment that supplements the tear film and reduces friction between the eyelids and cornea, thereby alleviating symptoms such as dryness, irritation, and discomfort, particularly overnight or in severe dry eye. Its primary role is as a topical ocular surface protectant and lubricant rather than as a pharmacologically active drug targeting a specific receptor or enzyme.
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