Drug intelligence / Profile preview

IAL-F

Development stage
Unknown
Lead developer
Fidia Farmaceutici
Modality
Recombinant Proteins and Enzymes
Administration
Intraocular
01

Overview

IAL-F is a cohesive ophthalmic viscoelastic device (OVD) containing 1.8% sodium hyaluronate derived from animal sources and is used primarily in cataract surgery (phacoemulsification with intraocular lens implantation) to maintain anterior chamber space, protect corneal endothelium, and facilitate surgical maneuvers. It is metabolized in the human body and has demonstrated efficacy in protecting against corneal endothelial cell loss, with safety comparable to other OVDs. The product is manufactured by Fidia Farmaceutici for use in ophthalmological procedures[3].

Brand names
IAL-F
Other names
IAL-F
02

Targets

RHAMM (Hyaluronan-mediated motility receptor)STAB2 (Stabilin-2)CD44 (CD44 antigen)ICAM1 (Intercellular Adhesion Molecule 1)

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