Drug intelligence / Profile preview

IBN-1

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

IBN-1 is an experimental **imidazolium-based compound** that has been described in the literature as a metal-free imidazolium salt and, in a separate materials context, as a main-chain imidazolium oligomer. Preclinical reports indicate antitumor activity in **hepatocellular carcinoma**, where IBN-1 inhibited proliferation, induced **G1-phase cell-cycle arrest**, and was associated with suppression of **survivin** and **cyclin-dependent kinases**. It has also been reported as a broad-spectrum antimicrobial imidazolium material active against multiple drug-resistant pathogens. The available evidence appears limited to early preclinical research, with no clear evidence of clinical development, regulatory approval, or established commercial manufacturing.

Other names
IBN-1IBN1IBN 1
02

Targets

CDK4 (Cyclin-dependent kinase 4)BIRC5 (Survivin)CDK6 (Cyclin-dependent kinase 6)

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